Suppression of adsorption properties of a z mutant of bacteriophage T4 by r mutations.
نویسنده
چکیده
The products of bacteriophage T4 r genes influence the organization of the phage-adsorption apparatus in a noncatalytic way.
منابع مشابه
Partial suppression of bacteriophage T4 ligase mutations by T4 endonuclease II deficiency: role of host ligase.
Endonuclease II-deficient, ligase-deficient double mutants of phage T4 induce considerably more deoxyribonucleic acid (DNA) synthesis after infection of Escherichia coli B than does the ligase-deficient single mutant. Furthermore, the double mutant can replicate 10 to 15% as well as wild-type T4, whereas the single mutant fails to replicate. When the E. coli host is also deficient in ligase, th...
متن کاملConstruction of the Recombinant Plasmid Expressing AID under the Control of Temperature-sensitive Promoter of Bacteriophage Lambda
Background and purpose: Activation-induced cytidine deaminase (AID) is a B-cell specific enzyme responsible for somatic hypermutation (SHM) and class switch recombination (CSR) of antibody genes within the B-cell follicle of peripheral lymphoid organs. Ectopic overexpression of the enzyme leads to mutations in non-B cells and Escherichia coli (E.coli) genes. However, induction of mutations in E...
متن کاملComparison of T4 Bacteriophage Adsorption and Progeny Production during Infection of Maturing Biofilms of Escherichia coli Wild-type and OmpC Mutants
Previous research into T4 bacteriophage infection of E. coli biofilms observed that during the fourth day of biofilm development, a transient substantial increase in T4 phage progeny production occurs. This increase was hypothesized to be due to over-expression of the outer membrane protein C (OmpC). OmpC is used by T4 bacteriophage for binding to the host cell, therefore its over-expression in...
متن کاملAntimutator mutants in bacteriophage T4 and Escherichia coli.
Antimutators are mutant strains that have reduced mutation rates compared to the corresponding wild-type strain. Their existence, along with mutator mutants that have higher mutation rates compared to the wild-type strain, are powerful evidence that mutation rates are genetically controlled. Compared to mutator mutants, antimutators have a very distinguishing property. Because they prevent norm...
متن کاملLigase-defective bacteriophage T4. I. Effects on mutation rates.
Temperature-sensitive mutations in bacteriophage T4 gene 30 (polynucleotide ligase) were examined for their effects on spontaneous and proflavine-induced frameshift mutagenesis in the rII and ac (acridine resistance) cistrons. Only small (fourfold or less) effects on mutation rates were observed, even when selection artifacts involving suppression of gene 30 mutations by rII mutations were take...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of virology
دوره 5 5 شماره
صفحات -
تاریخ انتشار 1970